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Patent for Method for Immunomodulation of using Aza-podophyllotoxin derivatives
By Ferraiuoli LLC
On July 16, 2024, the United States Patent and Trademark Office published patent number 12036270, titled Method for Immunomodulation of using Aza-podophyllotoxin derivatives, prosecuted by Ferraiuoli for its client SISTEMA UNIVERSITARIO ANA G. MÉNDEZ.
Aza-podophyllotoxin derivatives are modified versions of a natural compound found in the Mayapple plant. These derivatives have shown promise in cancer treatment due to their ability to kill cancer cells.
Certain aza-podophyllotoxin derivatives can stimulate the production of immune-related proteins like G-CSF and IL-6. These proteins play crucial roles in immune function.
If successful, this research could lead to:
New immunotherapies: Developing treatments that boost the immune system to fight diseases like cancer.
Improved vaccine efficacy: Enhancing the effectiveness of vaccines by stimulating a stronger immune response.
Treatment for autoimmune diseases: Potentially regulating an overactive immune system in autoimmune conditions.
Ferraiuoli LLC
Ferraiuoli LLC (FLLC) was founded in 2003 by the late Blas Ferraiuoli-Martínez, Eugenio Torres-Oyola and María Marchand-Sánchez. This group was then joined in 2004 by Fernando J. Rovira-Rullán, thus forming the founding core of FLLC. FLLC has grown exponentially since its founding from a law firm with three attorneys and a support staff of three to its current size of 54 attorneys with a support staff of 38. Also, FLLC has grown from initially being known as an intellectual property and corporate law boutique law firm to a multiservice law firm that handles most matters relevant to a business while continuing to earn praise for its leading intellectual property and corporate practices.
FLLC has been ranked as a leading law firm in Puerto Rico by the professional publication Chambers Latin America in intellectual property, corporate, bankruptcy, labor & employment, real estate, and tax law. Moreover, 17 FLLC partners have been ranked as leaders in their field by the same publication. 4 FLLC partners are ranked as leaders in Intellectual Property, no other firm has more than 2. This recognition in such a short period of time is a tribute to FLLC’s business model.
FLLC prides itself in doing its work faster and more cost-efficiently yet with the same quality as that of its main competitors. The founding name partners are available at all times to attend to client matters. Their work ethic sets the tone for the rest of the firm. FLLC’s founders’ goal has been steady from the outset: become one of the premier multiservice law firms in Puerto Rico.